Related Experiment Video
Updated: Oct 14, 2025

Laser Doppler Perfusion Imaging in the Mouse Hindlimb
Published on: April 18, 2021
Delayed perfusion evaluation in extremity trauma
Samuel Ferguson1, Tolga Turker1
1The University of Arizona, Department of Orthopaedics, Banner- University Medical Center, 1501 N. Campbell Ave., Floor 8, Tucson, AZ, 85719, USA.
Abstract:
After severe trauma to an extremity, it is essential to achieve a stable and non-infected wound in order to facilitate the best outcome following reconstruction. That said, timely, meticulous and adequate debridement is very important. To facilitate the best possible debridement of the wound, it is important to understand the tissue circulation. One available method to evaluate tissue circulation following extremity trauma is indocyanine green (ICG) angiography. Though playing an important role in flap surgeries, ICG may also provide information regarding the perfusion at the zone of injury while circulation quality diminishes. We present a case where ICG angiography initially showed good circulation in a mangled extremity, but later used in alternative way to display lack of flow in the same area of interest.
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