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Current Endoscopic Resection Techniques for Gastrointestinal Lesions: Endoscopic Mucosal Resection, Submucosal
Arthur Hoffman1, Raja Atreya2,3, Timo Rath2,3
1Department of Internal Medicine III, Aschaffenburg-Alzenau Clinic, Aschaffenburg, Germany.
Endoscopic resection of early cancer and dysplastic lesions is recommended, with various techniques available based on lesion characteristics. These endoscopic treatments are now considered first-line therapy for benign lesions.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
Background:
- Endoscopic resection of early-stage cancers and dysplastic lesions is a guideline-recommended procedure to reduce mortality.
- Established techniques like snare polypectomy and endoscopic mucosal resection (EMR) offer short procedure times and acceptable complication rates.
Purpose of the Study:
- To review the established and novel endoscopic resection techniques for gastrointestinal lesions.
- To highlight the evolving standards in endoscopic treatment for early cancer and benign lesions.
Main Methods:
- Review of established endoscopic resection techniques including snare polypectomy and EMR.
- Discussion of advanced techniques such as endoscopic submucosal dissection (ESD) and endoscopic full-thickness resection (EFTR) for challenging lesions.
Main Results:
- EMR allows en bloc resection of larger lesions with low complication rates.
- ESD and EFTR are emerging standards for lesions not amenable to EMR, enhancing en bloc resection rates.
Conclusions:
- Endoscopic resection is the recommended first-line therapy for benign lesions.
- A variety of endoscopic techniques are available, chosen based on specific lesion characteristics.
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