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Updated: Oct 14, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Novel isoindigo compound with aggregation-induced emission: Br-Br bonding joint restriction of intramolecular motion
Zhenyu Zhang1,2, Yu Sun3, Xu Zhao4
1Taiyuan University of Technology, Taiyuan, Shanxi Province, 030024, P. R. China.
Abstract:
6,6'-Dibromided tert-butyloxycarbonyl isoindigo (Br-TBOCII) has intense fluorescence in the solid state via excitation with aggregation-induced emission (AIE), contrary to the classic heavy-atom effect. The unique AIE mechanism is attributed to the Br-Br bonding joint restricting intramolecular motion. Furthermore, the water-soluble nanoparticles Br-TBOCII/Pluronic® 127, possess robust photostability, low toxicity and good cell imaging performance.

