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Association between peri-implantitis and cardiovascular diseases: A case-control study
I-Ching Wang1,2, Alice Ou1, Jeffery Johnston1,3
1Department of Periodontics & Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI.
Journal of Periodontology
|November 1, 2021
Summary
Cardiovascular disease (CVD) patients showed a trend toward more severe peri-implantitis. However, this association between peri-implantitis and CVD disappeared after accounting for other health factors.
Area of Science:
- Oral Health
- Cardiology
- Periodontology
Background:
- Peri-implantitis is a significant concern following dental implant placement.
- Cardiovascular diseases (CVD) represent a major global health issue.
- Understanding potential links between oral health and systemic conditions like CVD is crucial.
Purpose of the Study:
- To investigate the association between peri-implantitis and cardiovascular diseases (CVD).
- To evaluate the prevalence of peri-implantitis in patients with and without CVD.
Main Methods:
- 128 patients with dental implants were assessed for peri-implantitis.
- Patients were categorized into CVD and control groups.
- Radiographic bone loss (RBL) and clinical parameters were used for diagnosis and severity assessment.
- Multivariable logistic regression analyzed the association.
Main Results:
- A trend of higher peri-implantitis prevalence was observed in the CVD group (64.6% vs. 56.5%).
- Moderate to severe peri-implantitis (RBL ≥2 mm) was significantly more prevalent in the CVD group (48.8% vs. 30.4%).
- A crude significant association was found (OR=2.18, P=0.04), but this was not significant after controlling for confounders.
Conclusions:
- While a crude association exists, the link between peri-implantitis and CVD is not confirmed after adjusting for confounders.
- Further research with larger sample sizes and detailed confounder control is necessary.
- Investigating patient- and implant-related factors is essential for a comprehensive understanding.
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