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Case Report: Rotational Thromboelastometry in Taipan Envenomation.

Catherine L Tacon¹, Azhar Munas², Mark Little³

¹Department of Intensive Care, Cairns Hospital, Cairns, Australia.

The American Journal of Tropical Medicine and Hygiene

|November 1, 2021

Summary

Venom-induced consumption coagulopathy (VICC) from taipan snakebites can be dangerous. Rotational thromboelastometry (ROTEM) shows promise for assessing and managing VICC in clinical settings.

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Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

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Published on: June 4, 2020

Area of Science:

Toxicology
Hematology
Clinical Diagnostics

Background:

Venom-induced consumption coagulopathy (VICC) is a life-threatening complication of snake envenomation.
The Australian coastal taipan is one species known to cause VICC.
Rotational thromboelastometry (ROTEM) offers real-time analysis of blood clot formation.

Observation:

This study presents three cases of VICC following Australian coastal taipan envenomation.
ROTEM results were recorded and analyzed for each case.
VICC significantly impacts coagulation parameters as measured by ROTEM.

Findings:

ROTEM effectively captured the dynamic changes in coagulation during VICC.
Specific ROTEM parameters correlated with the severity of VICC.
The findings highlight ROTEM's sensitivity to VICC-related hemostatic abnormalities.

Implications:

ROTEM may serve as a valuable point-of-care tool for diagnosing and monitoring VICC.
This technology could guide timely and appropriate management of taipan envenomation.
Further research using ROTEM can enhance understanding and treatment strategies for VICC.