Related Experiment Video
Updated: Oct 14, 2025

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
Published on: October 4, 2019
[Retracted] miR‑506 functions as a tumor suppressor in glioma by targeting STAT3
Tao Peng1, Lixiang Zhou1, Ling Zuo2
1Department of Neurosurgery, First Bethune Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Abstract:
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the western blot assay data shown in Figs. 4D, 6B and 7F were strikingly similar to data appearing in different form in other articles by different authors. Furthermore, an independent investigation of this paper conducted by the Editorial Office unveiled possible anomalies associated with the cyclin D1 data presented in Fig. 4D. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, prior to its submission to Oncology Reports, the Editor has decided that this paper should be retracted from the Journal. The authors themselves requested that the paper be retracted. The Editor apologizes to the readership for any inconvenience caused. [the original article was published in Oncology Reports 35: 1057‑1064, 2016; DOI: 10.3892/or.2015.4406].
Related Concept Videos
Abnormal Proliferation
Loss of Tumor Suppressor Gene Functions
When the tumor suppressor genes develop mutations or are lost, cells start growing out of control, leading to cancer. However, a single functional copy of the tumor suppressor gene is enough for the cells to maintain their normal functions and cell...
MicroRNAs
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
mTOR Signaling and Cancer Progression
The mTOR pathway or the...
PI3K/mTOR/AKT Signaling Pathway

