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Published on: January 31, 2019
Agreement between oscillometric and direct blood pressure measurements in anesthetized captive chimpanzees (Pan
Christopher K Smith1, Anthony L Ashley1, Xiaojuan Zhu1
1From the Department of Small Animal Clinical Sciences (Smith, Cushing) and Office of Information and Technology (Zhu), College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996; and The Chattanooga Zoo, Chattanooga, TN 37404 (Ashley).
Objective:
To evaluate the level of agreement (LOA) between direct and oscillometric blood pressure (BP) measurements and the ability of oscillometric measurements to accurately detect hypotension in anesthetized chimpanzees (Pan troglodytes).
Animals:
8 captive, adult chimpanzees.
Procedures:
During prescheduled annual examinations, each chimpanzee underwent general anesthesia and patient monitoring for their examination, echocardiography for a concurrent study, and measurement of direct BP with the use of tibial artery catheterization and oscillometry with the use of a cuff placed around a brachium and a cuff placed around the second digit of the contralateral forelimb for the present study. Bland-Altman plots were generated to compare results for direct and oscillometric BP measurements. Mean bias and 95% LOAs were calculated for oscillometric measurements of systolic arterial pressure (SAP), diastolic arterial pressure (DAP), and mean arterial pressure (MAP) for each cuff site. Sensitivity and specificity in detecting hypotension were also determined for each cuff site.
Results:
There were 74 paired direct and brachial oscillometric measurements of each, SAP, MAP, and DAP and 66 paired direct and digit oscillometric measurements of each, SAP, MAP, and DAP. Only brachial oscillometric measurements of MAP had adequate sensitivity (78%) and specificity (95%) to accurately detect hypotension, and this technique also had the least mean bias (0.8 mm Hg; 95% LOA, -29 to 31 mm Hg).
Conclusions And Clinical Relevance:
Results indicated that brachial oscillometric measurement of MAP provided reasonable agreement with tibial arterial direct MAP measurement and performed well in diagnosing hypotension in anesthetized chimpanzees.
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