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Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

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Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
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Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Updated: Oct 14, 2025

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
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Optical coherence tomography and coronary revascularization: from indication to procedural optimization.

Rick Volleberg1, Jan-Quinten Mol1, Dirk van der Heijden2

  • 1Department of Cardiology, Radboudumc, Nijmegen, the Netherlands.

Trends in Cardiovascular Medicine
|November 3, 2021
PubMed
Summary

Optical coherence tomography (OCT) offers superior resolution for coronary interventions compared to angiography. This advanced imaging provides detailed plaque characterization and functional assessment, improving procedural planning and outcomes.

Keywords:
Coronary artery diseaseIntravascular imagingMyocardial infarctionOptical coherence tomographyPercutaneous revascularizationProcedural guidanceState-of-the-artVulnerable plaque

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Area of Science:

  • Cardiovascular Imaging
  • Interventional Cardiology

Background:

  • Coronary angiography is the standard for percutaneous coronary interventions but has limitations in resolution and plaque assessment.
  • Angiography provides a 2D view of the lumen, lacking information on plaque composition and functional stenosis severity.

Purpose of the Study:

  • To highlight the advantages of Optical Coherence Tomography (OCT) over traditional angiography in percutaneous coronary interventions.
  • To demonstrate OCT's capability for detailed plaque characterization and functional severity assessment.

Main Methods:

  • Utilizing Optical Coherence Tomography (OCT), an intracoronary imaging technique with superior spatial resolution.
  • Analyzing high-resolution OCT images for precise measurement of vascular and luminal dimensions.
  • Employing OCT data for computational models to assess functional stenosis severity.

Main Results:

  • OCT provides superior spatial resolution for detailed vascular and luminal dimension measurements.
  • High-resolution OCT imaging enables accurate assessment of anatomic stenosis severity and plaque characterization.
  • Periprocedural OCT imaging guides lesion preparation, stent implantation, and evaluation of complications.

Conclusions:

  • OCT is a powerful intracoronary imaging tool that surpasses angiography in detail and diagnostic capability.
  • OCT offers comprehensive data for planning, optimizing, and evaluating percutaneous coronary revascularization.
  • OCT has the potential to become an all-in-one imaging solution for interventional cardiology.