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Inflammatory bowel disease characterized by multisystemic eosinophilic epitheliotropic disease (MEED) in a horse in
Claudia Cruz Villagrán1, Debora Vogt1, Ashish Gupta1
1Department of Large Animal Clinical Sciences (Cruz Villagrán, Vogt) and Department of Veterinary Pathology (Gupta, Aburto), Western College of Veterinary Medicine, The University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
Abstract:
A 3-year-old Quarter Horse gelding was evaluated for chronic weight loss, diarrhea, and pruritus. Physical examination revealed several ulcerative lesions on the skin and mucosal membranes. Diagnostic imaging findings were consistent with enteritis, typhlitis, and colitis. Multisystemic eosinophilic epitheliotropic disease (MEED) was diagnosed upon necropsy. This disease may be considered a form of equine inflammatory bowel disease complex which can be challenging to diagnose, requiring histological assessment, and in some cases, the use of immunohistochemical markers. Key clinical message: Multisystemic eosinophilic epitheliotropic disease is challenging to diagnose but should be considered in horses with chronic weight loss that fail to respond to conventional treatment for concurrent diarrhea and skin lesions.
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