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Herpes simplex esophagitis in an immunocompetent host: a case report
Binit Upadhaya Regmi1, Ram Chandra Subedi1, Sujit Kumar Mandal1
1Department of Medicine, Shree Birendra Hospital, Nepalese Army Institute of Health Sciences, Kathmandu, Nepal.
Oxford Medical Case Reports
|November 3, 2021
Summary
Herpes Simplex virus (HSV) esophagitis is rare in healthy individuals. This case highlights successful treatment with acyclovir for severe dysphagia caused by HSV esophagitis in an immunocompetent young woman.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Virology
Background:
- Herpes Simplex virus (HSV) esophagitis is typically an opportunistic infection.
- It is rarely observed in immunocompetent individuals.
Observation:
- A young, immunocompetent female presented with severe dysphagia.
- Endoscopic and histopathological examination confirmed HSV esophagitis.
Findings:
- The patient experienced a complete recovery after a course of acyclovir.
- This indicates acyclovir's efficacy even in immunocompetent hosts.
Implications:
- This case expands the understanding of HSV esophagitis presentation in healthy individuals.
- It underscores the importance of considering HSV esophagitis in cases of severe dysphagia, regardless of immune status.
- Prompt diagnosis and antiviral treatment are crucial for favorable outcomes.

