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Updated: Oct 14, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
Adherence to fecal immunochemical test screening among adults at average risk for colorectal cancer
Deborah A Fisher1, Nicole Princic2, Lesley-Ann Miller-Wilson3
1Division of Gastroenterology, Duke University School of Medicine, 3100 Tower Blvd, Durham, NC, 27707, USA.
Purpose:
This study examined adherence to screening for fecal immunochemical test (FIT).
Methods:
Adults (≥ 50-75) with a FIT between 1/1/2014 and 6/30/2019 in MarketScan administrative claims were selected (index = earliest FIT). Patients were followed for 10 years pre- and 3 years post-index. Patients at increased risk for CRC or with prior screening were excluded. Year over year adherence was measured post-index.
Results:
Of 10,253 patients, the proportion adherent to repeat testing at year 2 was 23.4% and 10.6% at year 3. Of 76.6% not adherent in year 2, 5.4% were adherent in year 3.
Conclusion:
Results suggest adherence to FIT tests is poor, minimizing potential benefits. Future studies are needed to consider alternative test options and whether more choice will improve long-term adherence.
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