Related Experiment Video
Updated: Oct 14, 2025
09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
3.8K
Craniosynostosis Surgery for Increased Intracranial Pressure.
Megan E H Still1, Shreya Chidarala2, Abraham Alvarado1
1University of Florida, Lillian S. Wells Department of Neurosurgery.
The Journal of Craniofacial Surgery
|November 4, 2021
Summary
Craniosynostosis surgery improves symptoms of increased intracranial pressure (ICP), particularly in older children. Classic ICP signs like papilledema and headache showed the most improvement after surgical repair.
Area of Science:
- Pediatric Neurosurgery
- Craniofacial Surgery
- Developmental Biology
Background:
- Craniosynostosis involves premature fusion of cranial sutures, potentially leading to increased intracranial pressure (ICP).
- The response of ICP symptoms to surgical treatment for craniosynostosis can vary.
- Identifying specific symptoms that improve post-surgery is crucial for treatment planning.
Purpose of the Study:
- To identify signs and symptoms of increased ICP in craniosynostosis patients that are most likely to resolve after surgical intervention.
- To correlate patient age and specific clinical features with postoperative symptom improvement.
Main Methods:
- Retrospective analysis of 153 craniosynostosis patients (syndromic and non-syndromic) from January 2009 to June 2020.
- Evaluation of preoperative and postoperative data, including demographics, symptoms (headache, nausea, lethargy), and signs (papilledema, visual disturbances).
- Statistical analysis to determine correlations between patient characteristics, preoperative symptoms, and postoperative outcomes.
Main Results:
- Fifty-six patients with preoperative symptoms met inclusion criteria.
- Older age at surgery was significantly associated with a greater number of improved symptoms (P=0.015).
- Papilledema, headache, nausea, and irritability were the most frequently improved symptoms; optic nerve anomalies and feeding difficulties were least likely to improve.
Conclusions:
- Older children with craniosynostosis generally experience more symptom improvement after surgery.
- Classical signs of increased ICP are more responsive to surgical repair than developmental issues.
- These findings aid in surgical decision-making for symptomatic craniosynostosis patients.
More Related Videos
Related Concept Videos
01:22Sutures of the Skull
8.4K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
8.4K
01:14Cranial Bones: Superior and Posterior View
3.5K
The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
3.5K