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Bacterial Phylum Actinobacteria01:30

Bacterial Phylum Actinobacteria

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Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
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Related Experiment Video

Updated: Oct 14, 2025

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
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Actinomyces causing a brain abscess.

Alejandro Perez1, Gaurav Syngal2, Samreen Fathima3

  • 1Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas.

Proceedings (Baylor University. Medical Center)
|November 4, 2021
PubMed
Summary
This summary is machine-generated.

Actinomycosis, a rare bacterial infection, can cause serious complications like brain abscesses. Early diagnosis and treatment are crucial for managing this challenging granulomatous disease.

Keywords:
Actinomycesactinomycosisbrain abscesscentral nervous system

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Area of Science:

  • Infectious Diseases
  • Neurology
  • Microbiology

Background:

  • Actinomycosis is a chronic granulomatous infection caused by *Actinomyces israelii*.
  • It typically presents with oral-cervicofacial, chest wall, gastrointestinal, or genital tract manifestations.
  • The disease can be indolent and easily misdiagnosed as malignancy, necessitating a high index of suspicion.

Observation:

  • This case report details a rare instance of actinomycosis leading to a brain abscess.
  • The patient's presentation and diagnostic journey highlight the challenges in identifying this infection outside its common sites.
  • Cerebral involvement underscores the potential severity and systemic impact of *Actinomyces israelii*.

Findings:

  • Actinomycosis can manifest as a brain abscess, a severe central nervous system complication.
  • Diagnosis requires a high index of suspicion, especially when symptoms deviate from typical presentations.
  • Prompt identification and intervention are critical for favorable outcomes in complex actinomycosis cases.

Implications:

  • This case expands the known spectrum of actinomycosis presentations.
  • It emphasizes the importance of considering infectious etiologies, including actinomycosis, in unexplained neurological deficits.
  • Neuroimaging and microbiological confirmation are vital for diagnosing and managing brain abscesses caused by *Actinomyces*.