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Isolated ovarian vein thrombosis in COVID-19 infection

Udhayvir Singh Grewal1, Sreecharan Mavuram2, Nancy Bai3

  • 1Department of Internal Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana.

Proceedings (Baylor University. Medical Center)
|November 4, 2021
PubMed

Insights

COVID-19 increases thrombosis risk. This case study highlights a rare instance of ovarian vein thrombosis in a non-pregnant woman, linked to coronavirus disease-19, despite no inherited clotting disorders.

Area of Science:

  • Internal Medicine
  • Hematology
  • Infectious Diseases

Background:

  • COVID-19 is linked to heightened thrombosis risk.
  • Endothelial dysfunction and immune hyperactivation contribute to COVID-19-related coagulopathy.
  • Venous thromboembolism in COVID-19 typically manifests as pulmonary embolism or deep vein thrombosis.

Observation:

  • Ovarian vein thrombosis (OVT) is uncommon, primarily occurring postpartum.
  • This report details a case of OVT in a woman without prior pregnancy history.
  • The patient had a confirmed COVID-19 infection.

Findings:

  • The case presents a rare instance of COVID-19-associated ovarian vein thrombosis.
  • The patient was non-pregnant and showed no signs of inherited thrombophilia.
  • This suggests COVID-19 can induce OVT through mechanisms beyond typical risk factors.

Implications:

  • Highlights a rare thrombotic complication of COVID-19.
  • Expands understanding of COVID-19's impact on venous thromboembolism.
  • Suggests considering COVID-19 in unexplained OVT, even in non-pregnant individuals without inherited coagulopathy.

Keywords:
COVID-19COVID-19–associated coagulopathyovarian vein thrombosis

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