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Updated: Oct 14, 2025

A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
Sentiment Analysis for Necessary Preview of 30-Day Mortality in Sepsis Patients and the Control Strategies
Yanqun Zou1, Jian Wang1, Zheng Lei1
1Department of Critical Care Medicine, The First People's Hospital of Ziyang, Ziyang 641300, Sichuan, China.
Abstract:
This study was to preview the risk of 30-day mortality in sepsis patients using sentiment analysis. The clinical data of patients and nursing notes were collected from the Medical Information Mart for Intensive Care (MIMIC-III) database. The factors influencing 30-day mortality were analyzed using the Cox regression model. And, the prognostic index (PI) was estimated. The receiver operating characteristic (ROC) curve was used to determine the PI cut-off point and assess the prediction ability of the model. In total, 1844 of 3560 patients were eligible for the study, with a 30-day mortality of 37.58%. Multivariate Cox analysis showed that sentiment polarity scores, sentiment subjectivity scores, simplified acute physiology score (SAPS)-II, age, and intensive care unit (ICU) types were all associated with the risk of 30-day mortality (P < 0.05). In the preview of 30-day mortality, the area under the curve (AUC) of ROC was 0.78 (95%CI: 0.74-0.81,P < 0.001) when the cut-off point of PI was 0.467. The documented notes from nurses were described for the first time. Sentiment scores measured in nursing notes are associated with the risk of 30-day mortality in sepsis patients and may improve the preview of 30-day mortality.

