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Updated: Oct 14, 2025

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Published on: February 12, 2017
[Resection of Lung Cancer in Old Patients - Does Demographic Change Cause a Rethink?]
Klaus-Marius Bastian1, Aris Koryllos2, Ahmed Alkhatam1
1Klinik für Thoraxchirurgie, Florence-Nightingale-Krankenhaus, Akademisches Lehrkrankenhaus der Heinrich-Heine-Universität, Düsseldorf.
Older patients (over 75) tolerate thoracic surgery well, showing no increased complication rates and lower mortality when operated in specialized centers. Age alone should not prevent elderly patients from receiving optimal surgical care when indicated.
Area of Science:
- Thoracic Surgery
- Geriatric Medicine
- Oncology
Background:
- Demographic shifts in Germany show an aging population.
- The World Health Organization defines patients over 75 as elderly.
- The tolerance and outcomes of thoracic surgery in elderly patients remain unclear, often influenced by surgeon experience.
Purpose of the Study:
- To evaluate the safety and outcomes of thoracic surgery in elderly patients (over 75) compared to younger age groups.
- To determine if age alone is a limiting factor for thoracic surgery.
- To assess the impact of specialized centers on surgical outcomes in elderly patients.
Main Methods:
- Analysis of data from the German Thorax Register (2016-2018).
- Inclusion of 1357 patients, with 658 having Stage I-II lung cancer.
- Patients categorized into three age groups: <65, 65-75, and >75 years.
Main Results:
- Patients over 75 (Group III) did not exhibit increased postoperative complication rates (52.9%) compared to other groups.
- Group III showed better outcomes regarding pulmonary complications (pneumonia: 12.9%) than Group II (19.2%).
- Mortality was lowest in the German Thorax Register centers (1.3% for Group III) compared to the national average (3.78%).
- A higher proportion of VATS procedures were performed in German Thorax Register centers.
Conclusions:
- Elderly patients over 75 can safely undergo thoracic surgery with acceptable complication rates.
- Specialized centers demonstrate improved outcomes and lower mortality for elderly patients undergoing thoracic surgery.
- Age should not be the sole criterion for excluding elderly patients from thoracic surgery; suitability for surgery is key.
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