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Updated: Oct 14, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Mechanical Thrombectomy Outcomes in COVID-19 Patients With Acute Ischemic Stroke: A Narrative Review
Hadil Zureigat1, Muna Alhusban1, Miles Cobia2
1School of Medicine, University of Jordan, Amman, Jordan.
Insights
Mechanical thrombectomy (MT) for large-vessel occlusive (LVO) stroke in COVID-19 patients is associated with poorer outcomes. This review highlights challenges and negative impacts of COVID-19 on stroke patients undergoing MT.
Area of Science:
- Neurology
- Infectious Diseases
- Interventional Cardiology
Background:
- Coronavirus disease 2019 (COVID-19) increases thromboembolic event risk.
- Mechanical thrombectomy (MT) is a standard treatment for large-vessel occlusive (LVO) stroke.
- MT has been applied to stroke patients with COVID-19.
Purpose of the Study:
- To review outcomes of MT in COVID-19 patients with LVO stroke.
- To describe patient characteristics and stroke features in this population.
- To identify COVID-19-specific challenges in MT management.
Main Methods:
- Narrative review of published studies (March 2020 - February 2021).
- Analysis of patient characteristics, risk factors, and COVID-19 severity.
- Evaluation of stroke features and thrombectomy success rates.
Main Results:
- Evidence suggests poorer outcomes post-MT for COVID-19 patients.
- LVO in COVID-19 patients may present with distinguishing, challenging characteristics.
- Thrombectomy success data in this cohort is presented.
Conclusions:
- COVID-19 negatively impacts outcomes for acute ischemic stroke patients receiving MT.
- The long-term prognosis of stroke patients post-MT with COVID-19 remains undetermined.
- Clinicians should be aware of COVID-19-specific post-MT challenges.
Background:
Coronavirus disease 2019 (COVID-19) has been shown to associate with increased risk of thromboembolic events. Mechanical thrombectomy (MT) has long been used to effectively manage those with large-vessel occlusive (LVO) stroke and has similarly been implemented in the management of stroke in COVID-19 patients.
Review Summary:
The COVID-19 pandemic took the health care sector by a storm. Thus, less is known about MT outcomes in this population and evidence suggesting poor outcomes postthrombectomy for COVID-19 patients is accumulating. We provide a narrative on some of the published studies on the outcomes of MT in COVID-19 patients with LVO between March 2020 and February 2021. A description of patient characteristics, risk factors, COVID-19 infection severity, stroke features and thrombectomy success in this population is also presented as data from several studies show that LVO in COVID-19 patients may have some distinguishing characteristics that make management more challenging.
Conclusions:
The effect of COVID-19 on the long-term prognosis of stroke patients after thrombectomy is yet to be determined. The accumulating evidence from current studies indicates a negative impact of COVID-19 on outcomes in acute ischemic stroke patients who receive MT, irrespective of timely, successful angiographic recanalization. This review may help alert clinicians of some of the COVID-19-specific postthrombectomy challenges.
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