Related Experiment Video
Updated: Oct 14, 2025
Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
[Sclerosing hyperostotic bone disorders]
Daniela Kildal1, Rainer Braunschweig2, Matthias Schaal3
1Spitalzentrum Oberwallis, Pflanzettastr. 8, 3930, Visp, Schweiz. Daniela.Kildal@hopitalvs.ch.
Clinical/Methodical Issue:
Diagnosis of sclerosing and hyperostotic bone disorders (SHS) is challenging. The correct and early identification of SHS can have therapeutic, prognostic and, in case of genetic SHS with regard to the risk of inheritance, advisory consequences.
Standard Radiological Methods:
For diagnosis, radiographic examinations and supplementary computed tomography (CT) and magnetic resonance imaging (MRI) are used. These are of indicative nature. Definitive diagnosis is usually made by genetic differentiation.
Methodical Innovations:
In combination with the age of the affected person and the location of the osseous changes the characteristic image criteria are important. These are summarized in groups in this overview.
Practical Recommendations:
Projection radiography in two planes is the imaging modality of choice. CT and MR can detect additional differential diagnostic criteria and should be indicated when needed.
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