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Giant cell epulis.

Georgi Tchernev1, Lorraine Joseph Kandathil2, Nikhil Oliveira2

  • 1Onkoderma-Clinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606, Sofia, Bulgaria. georgi_tchernev@yahoo.de.

Wiener Medizinische Wochenschrift (1946)
|November 4, 2021
PubMed
Summary

Giant cell epulis, a benign oral lesion, can present as a large gingival mass. Early diagnosis and complete surgical excision are crucial to prevent recurrence of this reactive lesion.

Keywords:
Giant cell epulisPeripheral giant cell granulomaReactive oral lesion

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Area of Science:

  • Oral pathology
  • Surgical oncology

Background:

  • Giant cell epulis, also known as peripheral giant cell granuloma, is a reactive benign lesion often associated with local irritation or chronic trauma in the oral cavity.
  • Understanding the clinical presentation and diagnostic challenges of such lesions is vital for effective management.

Observation:

  • A 45-year-old male presented with a rapidly growing, painless gingival mass in the anterolateral maxilla, causing discomfort during mastication and bleeding.
  • Differential diagnoses included mucosal hemangioma and squamous cell carcinoma. Computed tomography revealed prior metal implants and mucosal hyperplasia adjacent to the lesion.

Findings:

  • Histopathological examination confirmed the diagnosis of giant cell epulis, showing multiple giant cells within a reactive stromal bed.
  • The presence of metal implants suggested a potential source of chronic irritation contributing to the lesion's development.

Implications:

  • Giant cell epulis has a significant potential for local recurrence, underscoring the need for thorough investigation and accurate diagnosis.
  • Complete surgical excision, coupled with the identification and removal of irritants, is essential for preventing relapse and ensuring optimal patient outcomes.