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Updated: Oct 14, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Comparison of hyoid bone morphology between obstructive sleep apnea patients and healthy individuals
Aida Kurbanova1, Bence Tamas Szabo2, Secil Aksoy1
1Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Near East University, Nicosia, Cyprus.
Objective:
We aimed to find morphological properties of the hyoid bone, which are predominant among the patients diagnosed with obstructive sleep apnoea (OSA), and compare them with healthy individuals.
Methods:
A total of 67 cone-beam computed tomography (CBCT) image sequences of patients (44 males, 23 females) diagnosed with OSA and a total of 70 multislice computed tomography (MSCT) data of non-OSA patients (45 males, 25 females) were selected in this study. DICOM images were imported into InVivo 5.1.2 (Anatomage) software. The position of the hyoid bone relative to the C3 and C4 cervical vertebrae, as well as its morphological type (B, V, U, H, D, HK-type) and its total volume was determined.
Results:
The volumetric values of the hyoid bone of OSA patients (2384.49 ± 682.073 mm3 ) were significantly (P < .001) lower compared to the values derived from non-OSA patients (2952.96 ± 932.5 mm3 ). The difference was independent of gender, and volumetric values showed a strong significant (P < .01) difference between male OSA and non-OSA (2709.18 ± 608.05; 3157.87 ± 926.5 mm3 ) and female OSA and non-OSA patients (1763 ± 242.51 2584; 2584.12 ± 840.21 mm3 ), as well. In the case of B and V-types, the volumetric values showed significant differences (P < .05), when the OSA (2300,77 ± 622; 2166 ± 312 mm3 ) and non-OSA patients were compared (2823,48 ± 780; 3216 ± 463 mm3 ).
Conclusion:
Our results suggest that the volume of the hyoid bone might be a potential biological marker for OSA, especially in the case of B and V hyoid bone types.
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