Related Experiment Video
Updated: Oct 14, 2025
Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
Published on: January 26, 2024
Lanthanide metal-organic framework as a paper strip sensor for visual detection of sulfonamide with smartphone-based
Jing Yan1, Jingfei Zhang1, Min Zhang1
1School of Chemistry and Molecular Engineering, Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, Shanghai Key Laboratory of Multidimensional Information Processing, Engineering Research Centre for Nanophotonics and Advanced Instrument (Ministry of Education), East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Abstract:
Antibiotic residues in aquatic environments have attracted wide attention. Considering the impacts on the ecosystem and human health, it is urgent to develop a rapid method for detecting antibiotic residues in the environment. In this work, a nanoscale lanthanide metal-organic framework Eu(TATB) with a stable red luminescence in aqueous solution is synthesized by the microemulsion method. Sulfamethazine (SMZ) is frequently most used in veterinary medicine as one of sulfonamides. Eu(TATB) can be used for sensitively and rapidly specific recognition of SMZ with low detection limit (0.67 μM) and eminent recyclability. In addition, a paper-based visual system for point-of-care (POC) monitoring SMZ is devised by both using filter paper embedded with Eu(TATB) and our developed portable smartphone-involved imaging cassette. The naked eyes can observe that the red luminescence of the paper sensor gradually fades away at the presence of SMZ. This provides a reliable and effective method for on-site detection of sulfonamide antibiotics in the field of environmental monitoring.
