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A case report of tuberculous constrictive pericarditis necessitating total pericardiectomy
Nooraldaem Yousif1, Abdulla Alnuwakhtha1, Abdulla Darwish2
1Mohammed Bin Khalifa Bin Sulman Al Khalifa Specialist Cardiac Centre (MKCC), Awali, Kingdom of Bahrain.
Insights
Tuberculous constrictive pericarditis (CP) poses diagnostic challenges. A novel hemodynamic assessment approach aided early diagnosis, leading to successful surgical intervention and symptom resolution.
Area of Science:
- Cardiology
- Infectious Diseases
- Surgical Pathology
Background:
- Constrictive pericarditis (CP) is a severe complication of tuberculous pericarditis, causing heart constriction due to inflammation and thickening.
- Accurate diagnosis and prompt intervention are vital for managing CP, presenting significant clinical challenges.
Observation:
- A case study of a Bahraini male with tuberculous lymphadenitis diagnosed with CP.
- Echocardiography showed suboptimal acoustic windows, and CT revealed no significant pericardial calcification.
- Hemodynamic assessment via right antecubital vein and right radial artery provided a novel diagnostic approach.
Findings:
- The patient underwent successful total pericardiectomy, revealing a thickened, stiff pericardium with abscesses and adhesions.
- Pericardial biopsy confirmed large caseating granulomas, indicative of tuberculosis.
- The patient experienced complete resolution of heart failure symptoms post-surgery.
Implications:
- This case highlights the difficulties in diagnosing CP, especially with suboptimal imaging.
- Early diagnosis and timely surgical intervention, like pericardiectomy, are crucial for favorable outcomes in CP.
- Novel hemodynamic assessment techniques can aid in diagnosing challenging CP cases.
Background:
Constrictive pericarditis (CP) is one of the most serious sequelae of tuberculous pericarditis, which is characterized by heart constriction secondary to intense pericardial inflammation and thickening. Several invasive and non-invasive diagnostic modalities are crucial to address the challenges of confirming the diagnosis of CP and to expedite timely intervention.
Case Summary:
This study reports the case of a Bahraini male with tuberculous lymphadenitis diagnosed with CP as a result of various evaluations. The patient underwent urgent total pericardiectomy and showed remarkable recovery with complete resolution of heart failure symptoms.
Discussion:
This case demonstrates the paramount importance of early diagnosis and treatment for patients with CP. In this unique case, the acoustic windows on echocardiography were suboptimal because of pericardial thickening. Further, computed tomography did not show significant calcification of the thickened pericardium. A novel approach of assessing haemodynamics through the right antecubital vein and right radial artery facilitated the accurate diagnosis of CP with confidence. Thereafter, successful pericardiectomy revealed a markedly thickened and stiff pericardium with many abscesses and dense adhesions encasing the heart, and pericardial biopsy showed large caseating granulomas. This case exemplifies the difficulty in diagnosing CP and the favourable outcomes achieved with well-timed surgical intervention.
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