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Updated: Oct 14, 2025

Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica
Published on: October 28, 2022
Break-even Analysis of Respirable Crystalline Silica (RCS) Exposure Interventions in the Construction Sector
Emile Tompa1, Amirabbas Mofidi, Chaojie Song
1Institute for Work & Health, Toronto, Ontario, Canada (Dr Tompa and Dr Mofidi); Department of Economics, McMaster University, Hamilton, Ontario, Canada (Dr Tompa); Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada (Dr Tompa, Dr Arrandale, and Dr Demers); Occupational Cancer Research Centre, Ontario Health, Toronto, Ontario, Canada (Dr Arrandale, Dr Demers, Ms Jardine, and Mr Song); School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada (Dr Davies); School of Occupational and Public Health, Ryerson University, Toronto, Ontario, Canada (Dr Tenkate).
Objective:
We investigated long-term economic impacts of respirable crystalline silica (RCS) removal interventions in the construction at the societal level.
Methods:
We estimated costs and benefits of two RCS exposure interventions, use of "respirators" and "wet method," over a 30-year time period. We identified economic impacts of the interventions under four different scenarios.
Results:
Under current practices, we estimated that approximately 125 lung cancer cases attributable to RCS exposure would arise in 2060. Under the full exposure removal scenario, we estimated there would be 53 new cases. Over the 30-year time period, the estimated cumulative averted cases are 787 and 482 for respirators and wet method, respectively, which amount to net benefits of $422.13 and $394.92 million.
Conclusions:
Findings provide important information for policymakers seeking to reduce the economic burden of occupational lung cancer in society.
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