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Updated: Oct 14, 2025

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Published on: April 9, 2021
Seroprevalence of SARS-CoV-2 Among Firefighters/Paramedics in San Francisco, CA
Megan Grant1, Robert Harrison, Arlene Nuñez
1University of California (Ms Grant, Dr Harrison, Dr Kurtz, Dr Shusterman); San Francisco Fire Department (Ms Nunez, Dr Phelps, Dr Brokaw), San Francisco, California.
Objectives:
Despite having close contact with the general public, members of the San Francisco Fire Department (SFFD) reported relatively few cases of COVID-19 during the first half of 2020. Our objective was to explore evidence for prior undetected infections by conducting a seroprevalence survey, and to document both risk and protective factors for prior COVID-19 infection.
Methods:
This cross-sectional study assessed workplace practices and exposures of SFFD personnel during the first 6 months of 2020 via questionnaire and documented prior COVID-19 infections by serologic antibody testing using an orthogonal testing protocol.
Results:
Of 1231 participating emergency responders, three (0.25%) had confirmed positive COVID-19 antibody results.
Conclusions:
Safe workplace practices, community public health intervention, and low community infection rates appear to have been protective factors for emergency responders in San Francisco during our study period.
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