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Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

102
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
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Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

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Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
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Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

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Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
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Assessment of blood pressure in brachial artery(two-step method)01:23

Assessment of blood pressure in brachial artery(two-step method)

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Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
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Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

73
The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
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Assessment of blood pressure in brachial artery(one-step method)01:15

Assessment of blood pressure in brachial artery(one-step method)

752
This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
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Related Experiment Video

Updated: Oct 14, 2025

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease
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Nonadherence in Hypertension: How to Develop and Implement Chemical Adherence Testing.

Dan Lane1,2, Alexander Lawson3, Angela Burns4

  • 1The Department of Chemical Pathology and Metabolic Diseases, Level 4, Sandringham Building, Leicester Royal Infirmary, United Kingdom (D.L., P.P., P.G.).

Hypertension (Dallas, Tex. : 1979)
|November 5, 2021
PubMed
Summary
This summary is machine-generated.

Chemical adherence testing reliably detects nonadherence to antihypertensive medication. This guidance offers recommendations for developing and implementing this crucial test for hypertension management.

Keywords:
adherencecomplianceguidelineshypertensionmass spectrometryurine

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Area of Science:

  • Pharmacology
  • Clinical Chemistry
  • Hypertension Management

Background:

  • Nonadherence to antihypertensive medication is prevalent, particularly in apparent treatment-resistant hypertension.
  • Routine detection of nonadherence is recommended by clinical guidelines.
  • Current chemical adherence testing methods lack standardization and widespread adoption.

Purpose of the Study:

  • To describe the principles of chemical adherence testing for hypertensive patients.
  • To provide recommendations for developing and implementing chemical adherence testing.
  • To standardize the approach to detecting medication nonadherence in hypertension.

Main Methods:

  • Review of principles for chemical adherence testing.
  • Development of recommendations for test implementation based on clinical scenarios.
  • Identification of key antihypertensive drugs for testing panels.
  • Discussion of technical, ethical, and practical considerations for testing.

Main Results:

  • Recommendations for when to perform chemical adherence testing: in resistant hypertension or suboptimal response to dual therapy.
  • A list of top antihypertensive drugs covering >95% of prescriptions is provided.
  • Information for mass spectrometry identification of these drugs is included.

Conclusions:

  • Chemical adherence testing is a valid method for detecting nonadherence in hypertension.
  • Standardized guidelines are needed to facilitate the development and implementation of these tests.
  • This guidance aims to assist clinicians and laboratories in establishing chemical adherence testing programs.