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Experiment, theory, and simulation of a flow-electrical-split flow thin particle separation device.

Kevin Petersen¹, Farhad Shiri¹, Tonguc Onur Tasci²

¹Department of Mechanical Engineering, University of Utah, Salt Lake, UT 84112, USA.

Journal of Chromatography. A

|November 5, 2021

Summary

This summary is machine-generated.

This study simulates a novel flow-electrical-split flow thin (Fl-El-SPLITT) device for particle separation. The simulation accurately predicts experimental results for DC fields and explains trends observed with AC fields and crossflows.

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Area of Science:

Microfluidics
Separation Science
Computational Modeling

Background:

Electrical Split Flow Thin (El-SPLITT) systems are used for particle separation.
Existing El-SPLITT theory does not account for AC fields or crossflows.
Accurate simulation of El-SPLITT devices is crucial for optimizing separation processes.

Purpose of the Study:

To develop and validate a novel flow-electrical-split flow thin (Fl-El-SPLITT) separation device simulation.
To investigate the influence of DC and AC electric fields, as well as crossflows, on particle separation.
To compare simulation predictions with experimental data for polystyrene particles of varying sizes.

Main Methods:

Developed a Matlab simulation for the Fl-El-SPLITT device.
Validated the simulation using existing El-SPLITT theory for DC fields.
Conducted experiments with 28 nm and 1000 nm polystyrene particles to compare with simulation results.
Investigated the effects of different outlet splitting planes (OSPs) and varying DC and AC field strengths.

Main Results:

The simulation accurately predicted transition points for DC fields with a 50:50 OSP.
Simulation results showed discrepancies with experimental data for 90:10 and 10:90 OSPs.
The simulation successfully explained trends observed in AC field testing and predicted particle fractions exiting ports.
Crossflow modeling showed some success, and DC voltage-dependent particle loss was observed during long-term testing.

Conclusions:

The developed Fl-El-SPLITT simulation effectively models the separation of polystyrene particles.
The simulation provides insights into the influence of DC, AC fields, and crossflows on El-SPLITT separation.
Further refinement of the simulation may be needed to fully capture experimental behavior across all OSPs and conditions.