Retracted: New Cu(II) coordination polymer inhibits cervical cancer development by regulating BRCA1 protein via...

A novel Cu(II)-based coordination polymer [chemical composition, {[CuL(CH₃CO₂)](H₂O)(DMF)}_n (1, DMF = N,N-dimethylformamide) was successfully prepared via Cu(NO₃)₂·3H₂O reaction with HL ligand in DMF and H₂O mixture by using a hetero-donor ligand 4-(bis(4-(4H-1,2,4-triazol-4-yl)phenyl)amino)benzoic acid (HL) featuring carboxylic acid and triazole groups. Reverse transcription-polymerase chain reaction (RT-PCR) was adopted to determine miR-9-5p expression in cervical cancer cells after compound treatment. Bioinformatic analysis and luciferase reporter assay were utilized to confirm miR-9-5p and BRCA1 interaction to discover the potential goal of miR-9-5p in cervical cancer cells. Cell Counting Kit-8 (CCK-8) and reactive oxygen species (ROS) detection kits were adopted to examine cancer cell proliferation and ROS accumulation after compound treatment.