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Sucrose Preference and Novelty-Induced Hypophagia Tests in Rats using an Automated Food Intake Monitoring System
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Sucrose solution concentration and the intermittent access induced consumption increase.

Roelof Eikelboom1, Randelle Hewitt1, Kerry L Adams1

  • 1Department of Psychology, Wilfrid Laurier University, Waterloo, ON, Canada.

Physiology & Behavior
|November 6, 2021
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Summary
This summary is machine-generated.

Intermittent access to preferred foods, like sucrose solutions, increases their value for rats. This effect can be long-lasting and impact consumption patterns, potentially relating to human eating behaviors.

Keywords:
BingeingCaloriesFeedingIntermittent accessRatsSucrose solutions

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Area of Science:

  • Behavioral neuroscience
  • Animal behavior
  • Physiological psychology

Background:

  • Animals often consume less preferred food with daily access compared to intermittent access.
  • Previous studies indicate that the frequency of food access influences consumption patterns.

Purpose of the Study:

  • To investigate the 'intermittency effect' on sucrose solution consumption in rats.
  • To determine how varying sucrose concentrations and access schedules affect intake.
  • To explore the long-lasting impact of intermittent access on food preference and value.

Main Methods:

  • Adult male rats were exposed to different sucrose concentrations (1%, 4%, 8%, 16%) under daily or every-third-day access schedules.
  • Consumption was measured over 23-hour periods.
  • Subsequent experiments manipulated access schedules and sucrose concentrations to assess lasting effects.

Main Results:

  • A significant intermittency effect, increasing consumption, was observed specifically with a 4% sucrose solution.
  • Rats with prior intermittent access (every third day) showed a pronounced elevation in 4% sucrose consumption when switched from daily access.
  • The heightened value for sucrose appeared long-lasting but was dependent on testing conditions.

Conclusions:

  • Intermittent access can induce a persistent increase in the perceived value of a preferred food for rats.
  • This effect is concentration-dependent and may require specific testing conditions to be fully evident.
  • Findings offer insights into the neurobiological underpinnings of food reward and may inform understanding of human obesity and binge eating disorders.