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Obesity prevalence in celiac disease in the United States from 2014 to 2018
Alyssa Drosdak1,2, Sagarika Satyavada3, Mayada Ismail3
1Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Addros014@gmail.com.
Insights
Obesity is increasingly prevalent in celiac disease (CD) patients. This study found rising obesity rates, particularly Class I, in adults diagnosed with CD between 2014 and 2018.
Area of Science:
- Gastroenterology
- Public Health
- Epidemiology
Background:
- Celiac disease (CD) is not typically linked with obesity.
- However, a significant number of CD patients are overweight or obese at diagnosis.
- Rising obesity rates in the general population necessitate an examination of obesity trends in CD patients.
Purpose of the Study:
- To investigate the prevalence and trends of obesity among adult patients diagnosed with celiac disease in the United States from 2014 to 2018.
Main Methods:
- Utilized a large electronic health record database from over 360 US hospitals.
- Included adult patients diagnosed with CD between 2014 and 2018 who underwent esophagogastroduodenoscopy.
- Analyzed obesity prevalence (BMI 30+) and categorized it into Class I, II, and III.
Main Results:
- Identified 13,410 adult CD patients in the study period.
- Overall obesity prevalence in CD patients was 45,000/100,000.
- Obesity prevalence across all classes (I, II, III) showed a rising trend from 2014 to 2018.
- Class I obesity was most prevalent, while Class II showed the highest increase.
Conclusions:
- Obesity is an emerging comorbidity with increasing prevalence in celiac disease patients.
- Clinicians must consider the rising rates of obesity when managing patients with CD longitudinally.
Abstract:
Celiac disease (CD) is not commonly associated with obesity; however, many patients are overweight or obese at time of diagnosis. As the number of people in the United States with obesity continues to rise, it is not known if the prevalence of obesity among patients with CD has also increased. This study utilized an electronic health record database incorporating over 360 individual hospitals in the United States (Explorys Incorporated, Cleveland, OH). Adult patients who had an esophagogastroduodenoscopy at least 1 day prior to reporting of CD from the years 2014 to 2018 formed the study population. From 2014 to 2018, 13,410 patients had a diagnosis of CD. The prevalence of obesity was 45,000/100,000 persons in this CD population. Prevalence of class I (BMI 30-34.9), II (BMI 35-39.9), and III (BMI > 40) obesity in patients with CD continued to rise over the 5-year span. Class I obesity had the highest prevalence and Class II the highest prevalence increase when obesity classes were compared. Clinicians should be aware of obesity as a comorbidity of increasing prevalence when providing longitudinal care for patients with CD.
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