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Primary biliary cholangitis: review for radiologists.
Matthew A Morgan1, Karthik M Sundaram2
1Department of Radiology, University of Pennsylvania Health System, 1 Silverstein, 3400 Spruce Street, Philadelphia, PA, USA. Matthew.Morgan@pennmedicine.upenn.edu.
Abdominal Radiology (New York)
|November 7, 2021
Summary
Primary biliary cholangitis is a rare bile duct disease. This review covers its causes, diagnosis, and imaging strategies for monitoring treatment response.
Area of Science:
- Hepatology and Radiology
Background:
- Primary biliary cholangitis (PBC) is a rare, progressive, chronic inflammation affecting medium and small bile ducts.
- Abdominal radiologists in tertiary or transplant settings may encounter PBC.
Purpose of the Study:
- To review current understanding of PBC pathophysiology and presentation.
- To outline diagnostic criteria and imaging strategies for PBC.
- To discuss treatment and imaging's role in monitoring treatment response.
Main Methods:
- Review of current literature on PBC pathophysiology, diagnosis, and treatment.
- Discussion of diagnostic imaging modalities.
- Inclusion of image-guided elastography for treatment monitoring.
Main Results:
- PBC diagnosis relies on specific criteria and imaging findings.
- Imaging plays a crucial role in assessing disease progression and treatment efficacy.
- Image-guided elastography is an emerging tool for monitoring treatment response.
Conclusions:
- Accurate diagnosis and monitoring of PBC are essential for patient management.
- Radiologists play a key role in the multidisciplinary approach to PBC.
- Advanced imaging techniques improve the assessment of treatment effectiveness in PBC.
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