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Updated: Oct 14, 2025

A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues
Published on: December 5, 2016
The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A
Weiwei Sun1, Bin Zhang2, Qingli Bie2
1Institute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining, Shandong, China.
Abstract:
The biological role of RNA methylation in stem cells has attracted increasing attention. Recent studies have demonstrated that RNA methylation plays a crucial role in self-renewal, differentiation, and tumorigenicity of stem cells. In this review, we focus on the biological role of RNA methylation modifications including N6-methyladenosine, 5-methylcytosine, and uridylation in embryonic stem cells, adult stem cells, induced pluripotent stem cells, and cancer stem cells, so as to provide new insights into the potential innovative treatments of cancer or other complex diseases.
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