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COVID-19 diagnosis from routine blood tests using artificial intelligence techniques.

Samin Babaei Rikan1, Amir Sorayaie Azar1, Ali Ghafari2

  • 1Department of Computer Engineering, Urmia University, Urmia, Iran.

Biomedical Signal Processing and Control
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A deep neural network model accurately diagnosed COVID-19 using routine blood tests. This artificial intelligence tool offers fast, reliable results to aid clinicians in timely diagnosis during the pandemic.

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Blood testsCOVID-19Deep learningDiagnosisMachine learning

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Area of Science:

  • Medical Informatics
  • Computational Biology
  • Machine Learning in Healthcare

Background:

  • The COVID-19 pandemic necessitates rapid and accurate diagnostic tools.
  • Emerging SARS-CoV-2 variants increase transmission rates, highlighting the need for efficient detection.
  • Automated diagnostic systems can significantly support clinical decision-making.

Purpose of the Study:

  • To develop and evaluate machine learning and deep learning models for COVID-19 diagnosis.
  • To assess the efficacy of using routine laboratory blood tests for automated COVID-19 detection.
  • To identify the most effective model for accurate and rapid COVID-19 diagnosis.

Main Methods:

  • Utilized three routine laboratory blood test datasets.
  • Implemented seven machine learning and four deep learning models.
  • Employed Pearson, Spearman, and Kendall correlation coefficients and four-fold cross-validation.
  • Applied statistical t-tests and AI interpretation for feature analysis.

Main Results:

  • The deep neural network (DNN) model consistently outperformed other models across all datasets.
  • The DNN model achieved high performance metrics, including average accuracy (up to 93.16%), specificity (up to 93.02%), and AUC (up to 93.20%).
  • Identified key features contributing to the DNN model's diagnostic accuracy.

Conclusions:

  • The proposed DNN model demonstrates significant potential as a supplementary tool for COVID-19 diagnosis.
  • This AI-driven approach offers clinicians a fast and highly accurate method for identifying positive COVID-19 cases.
  • The study validates the use of routine blood tests and AI for efficient pandemic response.