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Thyroid Gland Disease as a Comorbid Condition in COPD.
Aziz Gumus1, Neslihan Ozcelik1, Bilge Yilmaz Kara1
1Recep Tayyip Erdogan University, Faculty of Medicine, Department of Chest Disease, Rize, Turkey.
Thyroid gland diseases (TGD) are common in patients with chronic obstructive pulmonary disease (COPD), affecting 22% of individuals studied. These thyroid abnormalities, including euthyroid sick syndrome, are frequently observed and warrant further investigation in COPD management.
Area of Science:
- Pulmonary Medicine
- Endocrinology
Background:
- Chronic obstructive pulmonary disease (COPD) is a leading global cause of illness and death.
- COPD involves progressive airway inflammation with systemic effects and comorbidities.
- Thyroid diseases are underrecognized comorbidities in COPD patients.
Purpose of the Study:
- To determine the prevalence of thyroid gland disease (TGD) in COPD patients.
- To identify factors associated with TGD in this population.
Main Methods:
- 309 COPD patients (297 male) underwent spirometry and thyroid function tests during stable periods.
- Thyroid gland diseases were diagnosed through face-to-face meetings and medical file reviews.
Main Results:
- Thyroid disease was identified in 68 (22%) of the COPD patients.
- Specific diagnoses included hypothyroidism (2%), euthyroidism (15%), and hyperthyroidism (5%).
- No correlation was found between airflow limitation severity and TGD prevalence.
Conclusions:
- Thyroid abnormalities are frequently observed in individuals with COPD.
- Common TGDs include euthyroid multinodular goiter, euthyroid sick syndrome (ESS), and toxic multinodular goiter.
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