Postoperative Candida Infection following Complex Periocular Reconstruction.

Area of Science:

• Dermatology
• Infectious Diseases
• Surgical Oncology

Background:

• Postoperative Candida infection is an uncommon complication following cutaneous surgery.
• Immunocompromised status and extensive reconstructive procedures may increase risk.
• Prophylactic antibiotics can sometimes alter the microbial balance, potentially leading to opportunistic infections.

Observation:

• A 59-year-old human immunodeficiency virus (HIV)-positive patient developed a Candida infection post-eyelid surgery.
• The infection presented as erythema and pustules within the surgical site.
• Initial broad-spectrum antibiotic treatment was ineffective.

Findings:

• Wound culture confirmed *Candida albicans* infection.
• The patient responded well to targeted antifungal therapy with fluconazole and clotrimazole.
• Successful graft healing was achieved despite the infection.

Implications:

• Early diagnosis and appropriate antifungal treatment are critical for managing postoperative Candida infections.
• Awareness of risk factors, including immunosuppression and complex surgeries, is essential.
• This case underscores the need for vigilance in identifying non-bacterial causes of surgical site infections.