Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Accessory Structures of the Eye01:17

Accessory Structures of the Eye

2.1K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
2.1K
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

178
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
178
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

4.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
4.4K
Surface Membrane Barriers01:18

Surface Membrane Barriers

1.7K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.7K
Glaucoma: Overview01:25

Glaucoma: Overview

961
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
961
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

12.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Shenfu Decoction Extends Survival Time of Seawater-Induced Hypothermia in Rats: The Role of Metabolomics and Gut Microbiota.

Current drug metabolism·2026
Same author

Getting fairer over time? Assessing changes in health technology funding processes using the accountability for reasonableness (A4R) framework.

The European journal of health economics : HEPAC : health economics in prevention and care·2026
Same author

Ultrasound-Guided Radiofrequency Ablation of Benign Thyroid Nodules: 2-Year Follow-Up Results from a Single Center.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine·2026
Same author

High-Resolution Spatiotemporal Characterization of PM<sub>2.5</sub> across On-Road Microenvironments Using Large-Scale Taxi-Based Mobile Monitoring in a Chinese City.

Environmental science & technology·2026
Same author

An Ecological Impact Assessment Framework and Integrated Management Pathway for Large-Scale Chemical Mosquito Control in Urban Areas.

ACS environmental Au·2026
Same author

Lipase Immobilized in Hollow Mesoporous Carbon Spheres: Enzymatic Properties and Applications in the Production of Geranyl Acetate.

Journal of agricultural and food chemistry·2026

Related Experiment Video

Updated: Oct 14, 2025

Conjunctival Commensal Isolation and Identification in Mice
07:52

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

4.6K

Microbiota and Ocular Diseases.

Wei Xue1, Jing Jing Li1, Yanli Zou1,2

  • 1State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, China.

Frontiers in Cellular and Infection Microbiology
|November 8, 2021
PubMed
Summary
This summary is machine-generated.

The gut microbiome influences eye health, impacting conditions like uveitis and glaucoma. Research explores the "gut-eye axis" for potential therapies targeting gut microbes to reduce eye inflammation.

Keywords:
gut microbiomegut-eye axismicrobial therapeuticsmultiomicsophthalmic diseases

More Related Videos

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

30.3K
Induction of Ocular Surface Inflammation and Collection of Involved Tissues
06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

2.4K

Related Experiment Videos

Last Updated: Oct 14, 2025

Conjunctival Commensal Isolation and Identification in Mice
07:52

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

4.6K
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

30.3K
Induction of Ocular Surface Inflammation and Collection of Involved Tissues
06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

2.4K

Area of Science:

  • Microbiology
  • Ophthalmology
  • Immunology

Background:

  • Emerging research links gut microbiota composition and function to non-digestive organ disorders.
  • The microbial community's impact on ocular diseases is increasingly recognized.

Purpose of the Study:

  • To review current literature on microbiota analysis techniques.
  • To explore the role of commensal microbes in ophthalmic diseases.
  • To discuss the gut-eye axis and its therapeutic implications for ocular inflammation.

Main Methods:

  • Literature review of studies on microbiota analysis.
  • Examination of research on gut microbiota and ophthalmic conditions.
  • Analysis of the gut-eye axis hypothesis.

Main Results:

  • Significant associations found between gut microbiota and various ocular disorders.
  • Commensal microbes play a role in autoimmune uveitis, age-related macular degeneration, and glaucoma.
  • The gut-eye axis is a plausible biological connection.

Conclusions:

  • Targeting the gut microbiota presents a potential therapeutic strategy for ocular inflammation.
  • Further research into the gut-eye axis could lead to novel treatments for eye diseases.