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Updated: Oct 14, 2025

Mouse Model of Pressure Ulcers After Spinal Cord Injury
Published on: March 9, 2019
Factors associated with pressure ulcer onset after knee replacement
Cristiana Forni1, Nicola Cerantola1, Gianfranco Ferrarelli1
1Servizio di Assistenza Infermieristica, Tecnica e Riabilitativa, IRCCS - Istituto Ortopedico Rizzoli, Bologna, Italia.
Objective:
The aim of this study was to find the rate of pressure ulcers (PUs) in patients with knee replacements and identify predictive factors. The ability of the Braden scale to predict the onset of PUs was also investigated.
Method:
A retrospective prognostic cohort study was carried out involving all consecutive patients undergoing knee replacement surgery. The data were collected from patient records. The variables collected were grouped into two categories: those connected to the patient's own characteristics; and those linked to the care methods used.
Results:
The total number of patients included in the study was 565. Of these, 2.3% had developed a PU: 0.5% at the heel and 1.8% at the sacrum. Multivariate analysis showed that the variables actually correlated to the outcome were age (p=0.074; odds ratio (OR)=1.08), body mass index (BMI, p=0.037; OR=1.13) and Braden scale (p=0.029; OR=0.72). A combination of these three parameters showed better predictivity of PUs (area under the curve (AUC) 84%).
Conclusion:
Age, BMI and preoperative Braden score were shown to be independent predictive factors of the onset of PUs in patients with knee replacements. The combined use of all three variables increased the ability to identify the patients at most risk of developing a PU.
Declaration Of Interest:
The study was financed by the Professional Nurse Register of Bologna as winner of a competition for research projects in the province of Bologna. The authors declare no conflicts of interest.
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