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Published on: November 9, 2019
Gold-Catalyzed Reactions Towards Diversity: From Simple Substrates to Functionalized Carbo- and Heterocycles
1Côte d'Azur University, Institut de Chimie de Nice, UMR 7272 CNRS, Valrose Park, Faculty of Sciences, 06108, Nice Cedex 2, France.
Abstract:
The field of gold catalysis has been in constant expansion during the last twenty years. Based on the precept of π-activation of unsaturated simple substrates, several new rearrangements have been discovered, implying aryl, alkyne, alkene or keto derivatives as key partners. In this personal account, the main contributions in the field of gold catalysis from our group will be highlighted, emphasizing the recent reports, starting from 1,6- and 1,5-enynes and then moving to keto-ynes derivatives. The gold-catalyzed reactions will be presented starting from classical skeletal rearrangements (cycloisomerization) and then domino processes. In each part, the presentation of asymmetric versions will be highlighted.
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