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Related Concept Videos

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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The Thyroid Gland01:23

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
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Major Hormones and Their Functions01:27

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Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
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The Parathyroid Glands00:59

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The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
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Related Experiment Video

Updated: Oct 14, 2025

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
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Levothyroxine-Induced Pseudotumor Cereberi.

Farhat Abbas1, Muzamil Latief2

  • 1Department of Pathology, GMC, Srinagar, Kashmir, India.

Neurology India
|November 8, 2021
PubMed
Summary

A rare case of Pseudotumor cerebri (PTC) was induced by Eltroxin (levothyroxine). Discontinuation of this common thyroid medication led to a dramatic patient recovery, highlighting a unique drug-induced neurological complication.

Keywords:
Diplopiaheadacheintracranial tensionpseudotumor cerebri

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Area of Science:

  • Neurology
  • Endocrinology

Background:

  • Intracranial hypertension (IH) presents with diverse symptoms, from headaches to severe neurological deficits.
  • The rate of intracranial tension rise is a critical clinical factor.
  • Pseudotumor cerebri (PTC) is linked to various syndromes, toxins, and medications.

Observation:

  • This report details a unique case of drug-induced PTC.
  • The patient developed PTC while using Eltroxin (levothyroxine), a widely prescribed thyroid medication.
  • The presentation was unusual due to the rarity of this specific drug association.

Findings:

  • Discontinuation of levothyroxine resulted in a rapid and significant improvement in the patient's condition.
  • This suggests a direct causal link between levothyroxine and the development of PTC in this individual.

Implications:

  • Clinicians should consider levothyroxine as a potential cause of PTC, especially in patients with unexplained intracranial hypertension.
  • This case underscores the importance of a thorough medication review in diagnosing and managing neurological conditions.
  • Further investigation into the mechanisms of levothyroxine-induced PTC may be warranted.