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Isolated Enhancement Effect is the Only MRI Finding for Wernicke's encephalopathy
Shuang He1, Yin-Yan Xu1, Shuai Chen1
1Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
Neurology India
|November 8, 2021
Summary
Wernicke
Area of Science:
- Neuroscience
- Radiology
Background:
- Wernicke's encephalopathy (WE) is an acute neuropsychiatric condition caused by thiamine (vitamin B1) deficiency.
- Classic WE symptoms include altered mental status, ophthalmoplegia, and ataxia, though these appear together in only 20% of cases.
Observation:
- A 44-year-old female patient developed WE after bowel surgery and fasting.
- Neuroimaging revealed unique symmetrical abnormalities in the mammillary bodies and dorsal midbrain.
Findings:
- These specific abnormalities were only visible on contrast-enhanced brain MRI.
- Standard MRI sequences did not show these particular findings.
Implications:
- Contrast-enhanced MRI may be crucial for diagnosing subtle WE cases.
- This case highlights the importance of considering WE in patients with relevant risk factors and atypical imaging findings.
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