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Updated: Oct 14, 2025

In-depth Physiological Analysis of Defined Cell Populations in Acute Tissue Slices of the Mouse Vomeronasal Organ
Published on: September 10, 2016
Phasic spiking in vasopressin neurons: How and Why
1Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.
Abstract:
The plain title might have been an almost retro sounding grumpy retort, but it has inspired a journey of sorts, and something along the way I hope you won't have come across before. An opinionated exploration of the distinctive phasic spiking patterns of magnocellular vasopressin neurons of the supraoptic and paraventricular nuclei of the hypothalamus. A mostly life essential population of neurons that signal the kidneys to regulate water loss in response to signals that encode plasma volume and osmotic pressure, as well as regulating blood pressure, and possibly metabolism and social behaviour. The viewpoint of a modeller shorn of any explicit maths.
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