Search research articles

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Challenges and considerations in forensic entomology: A comprehensive review.

Journal of forensic and legal medicine·2025

Same author

Robotics in Joint Replacement Surgery.

Journal of orthopaedic case reports·2024

Same author

Fabrication of Mesoporous Materials Based on Supramolecular Self-Assembly of Guanosine Monophosphonate-Nickel Chloride (GMP-Ni) for High-Performance Hybrid Supercapacitors.

ACS applied materials & interfaces·2024

Same author

Exploring antibiofilm potential of some new imidazole analogs against <i>C. albicans:</i> synthesis, antifungal activity, molecular docking and molecular dynamics studies.

Journal of biomolecular structure & dynamics·2024

Same author

Early Outcomes of Modified Technique of Mobile Bearing Unicondylar Knee Replacement.

Indian journal of orthopaedics·2023

Same author

Menthol Inhibits <i>Candida albicans</i> Growth by Affecting the Membrane Integrity Followed by Apoptosis.

Evidence-based complementary and alternative medicine : eCAM·2022

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Oct 14, 2025

Mitochondria and Endoplasmic Reticulum Imaging by Correlative Light and Volume Electron Microscopy

Mitochondria and Endoplasmic Reticulum Imaging by Correlative Light and Volume Electron Microscopy

Published on: July 20, 2019

Aggregation induced emission (AIE) materials for mitochondria imaging.

Satish Deshmukh¹, Madan R Biradar², Kiran Kharat³

¹Department of Chemistry, MSPMs' Deogiri College, Aurangabad, India.

Progress in Molecular Biology and Translational Science

|November 9, 2021

Summary

Aggregation-induced emission (AIE) probes offer sensitive and specific mitochondrial labeling for cell biology. This review details three main AIEgen types for mitochondrial staining and sensing applications.

Keywords:

AIEgens Bioimaging Mitochondria Tetraphenylethene Triphenylamine Triphenylphosphine

More Related Videos

Specific Labeling of Mitochondrial Nucleoids for Time-lapse Structured Illumination Microscopy

Specific Labeling of Mitochondrial Nucleoids for Time-lapse Structured Illumination Microscopy

Published on: June 4, 2020

Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells

Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells

Published on: July 22, 2013

Related Experiment Videos

Last Updated: Oct 14, 2025

Mitochondria and Endoplasmic Reticulum Imaging by Correlative Light and Volume Electron Microscopy

Mitochondria and Endoplasmic Reticulum Imaging by Correlative Light and Volume Electron Microscopy

Published on: July 20, 2019

Specific Labeling of Mitochondrial Nucleoids for Time-lapse Structured Illumination Microscopy

Specific Labeling of Mitochondrial Nucleoids for Time-lapse Structured Illumination Microscopy

Published on: June 4, 2020

Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells

Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells

Published on: July 22, 2013

Area of Science:

Cell Biology
Biochemistry
Biotechnology

Background:

Mitochondria are vital energy-producing organelles in eukaryotic cells.
Key mitochondrial functions include autophagy, reactive oxygen species (ROS) detection, and involvement in cell death.
Photodynamic therapy in cancer cells is another critical area of mitochondrial research.

Purpose of the Study:

To discuss three major types of aggregation-induced emission (AIE) probes used for mitochondrial staining.
To highlight the advantages of AIE probes, including specificity and sensitivity, for mitochondrial labeling.
To explore the structural motifs and applications of different AIEgens in mitochondrial detection and sensing.

Main Methods:

Review of literature on AIEgens for mitochondrial imaging.
Categorization of AIE probes based on structural motifs: tetraphenylethene (TPE)-based, triphenylphosphine (TPP) and triphenylamine (TPA)-based, and miscellaneous AIEgens.
Discussion of the application of these AIEgens in bioimaging, cell analysis, and cancer therapy.

Main Results:

Tetraphenylethene (TPE)-based AIEgens are widely used in bioimaging due to their simple structure.
AIEgens like triphenylphosphine (TPP) and triphenylamine (TPA) serve as novel building blocks for specific bio-probes.
These probes demonstrate utility in lipid droplet imaging, cell viability assays, and photodynamic cancer cell removal.

Conclusions:

AIE probes are effective tools for sensitive and specific mitochondrial labeling.
Different structural classes of AIEgens offer versatile applications in mitochondrial research and diagnostics.
The development of AIEgens continues to advance bioimaging and therapeutic strategies targeting mitochondria.