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Updated: Oct 14, 2025

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
18F-DCFPyL PET/CT in Metastatic Renal Cell Carcinoma
Geoffrey M Currie1, Marko Trifunovic2, Jui Liu2
1Faculty of Science, Charles Sturt University, Wagga Wagga, Australia; gcurrie@csu.edu.au.
Abstract:
Targeted molecular imaging with PET uses chemical ligands that are peptides specifically targeting a receptor of interest. Prostate-specific membrane antigen (PSMA) is substantially upregulated in prostate cancer but is also expressed in the neovascular tissue of several malignancies, including renal cell carcinoma (RCC). Radiolabeled peptide targets for PSMA may be helpful in detecting metastatic RCC lesions. We present a case of incidental detection of RCC metastatic disease with PSMA-targeted PET, and we explore potential use for deliberate evaluation of RCC with PSMA-targeted tracers.
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