Related Experiment Video
Updated: Oct 14, 2025

Author Spotlight: Establishing Germ-Free Zebrafish for Microbiota-Host Relationship Studies
Published on: April 12, 2024
A systematic review of advances in intestinal microflora of fish
Chang Liu1, Li-Ping Zhao1, Yan-Qin Shen2
1Wuxi Medical School of Jiangnan University, Wuxi, China.
Abstract:
Intestinal flora is closely related to the health of organisms and the occurrence and development of diseases. The study of intestinal flora will provide a reference for the research and treatment of disease pathogenesis. Upon hatching, fish begin to acquire a microbial community in the intestine. In response to the environment and the host itself, the fish gut eventually develops a unique set of microflora, with some microorganisms being common to different fish. The existence of intestinal microorganisms creates an excellent microecological environment for the host, while the fish symbiotically provides conditions for the growth and reproduction of intestinal microflora. The intestinal flora and the host are interdependent and mutually restrictive. This review mainly describes the formation of fish intestinal flora, the function of normal intestinal flora, factors affecting intestinal flora, and a series of fish models.

