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Updated: Oct 14, 2025

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
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[Herpes simplex as a complex interdisciplinary problem. Clinical case].

D R Yunusova1, E N Silantieva2, E I Yunusova2

  • 1Kazan State Medical University of the Ministry of Health of the Russian Federation, Kazan, Russia.

Stomatologiia
|November 9, 2021
PubMed
Summary
This summary is machine-generated.

Panavir effectively treated severe recurrent herpes simplex virus (HSV) infections affecting the oral mucosa and genital area. This antiviral therapy demonstrated rapid symptom resolution and good tolerability with no adverse effects.

Keywords:
anogenital herpetic viral infectionimmunityoral herpetic infectionoral mucosa

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Area of Science:

  • Virology
  • Dermatology
  • Infectious Diseases

Background:

  • Recurrent herpes simplex virus (HSV) infections present significant challenges in managing oral and genital lesions.
  • Combined infections of the oral mucosa and genital area require effective and well-tolerated treatment options.

Purpose of the Study:

  • To evaluate the efficacy of Panavir in treating patients with co-occurring oral and genital herpetic lesions.
  • To assess the safety and tolerability of Panavir in this patient population.

Main Methods:

  • A case study involving a 42-year-old patient with combined oral and genital herpetic lesions.
  • Diagnostic methods included clinical examinations (luminescent stomatoscopy, dermatovenerological assessment) and laboratory tests (blood/urine analysis, microscopy, PCR).
  • Treatment involved a regimen of Panavir injections and topical applications to affected areas.

Main Results:

  • Panavir treatment led to rapid resolution of the inflammatory infectious process.
  • Significant reduction in lesion area and subjective symptoms (discomfort, pain) observed by day three.
  • Complete regression of oral and perianal lesions within seven days of initiating therapy.

Conclusions:

  • Panavir demonstrates high efficacy in the complex treatment of severe recurrent herpes virus infections of the oral mucosa and genital area.
  • The drug is well-tolerated, with no reported side effects.
  • Panavir treatment contributes to an extended remission period for patients with severe herpetic lesions.