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Updated: Oct 14, 2025

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
Published on: November 3, 2012
[Herpes simplex as a complex interdisciplinary problem. Clinical case]
D R Yunusova1, E N Silantieva2, E I Yunusova2
1Kazan State Medical University of the Ministry of Health of the Russian Federation, Kazan, Russia.
The Purpose Of The Study:
To show the effectiveness of the use of the drug Panavir in patients with a combined clinical manifestation of viral herpetic lesions of the oral mucosa and genital area.
Material And Methods:
Patient S., 42 years old, complained of discomfort, pain and rashes in the mouth and on the genitals. To assess the patient's condition, clinical (dental examination using luminescent stomatoscopy and dermatovenerological examination) and laboratory methods were used: clinical blood and urine tests, microscopy of smears from the urethra, cervical canal, vagina, rectum and PCR-examination of the discharge from the elements of the lesion of the oral mucosa, urethra, cervical canal and the contents of vesicular rashes on the skin of the perianal area.
Results:
The prescribed antiviral treatment with the inclusion of 0.004% Panavir scheme in the form of injections and drugs for topical use on the oral mucosa, genitals and on the skin, made it possible to quickly achieve a resolution of the inflammatory infectious process. On the third day after the start of therapy, the patient noted a decrease in the area of inflammation. Subjective sensations in the form of discomfort during urination, burning and soreness in the foci were leveled. After 7 days, the foci in the mouth and on the skin of the perianal area completely regressed.
Conclusion:
The use of Panavir in the complex treatment of severe forms of recurrent herpes virus lesions of the oral mucosa and genital area has shown its high efficiency, good tolerability, no side effects and an increase in the remission period.
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