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Updated: Oct 14, 2025

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Near-Infrared Temperature Measurement Technique for Water Surrounding an Induction-heated Small Magnetic Sphere
Published on: April 30, 2018
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Phase-independent thermometry by Z-spectrum MR imaging
Alessandro M Scotti1,2, Frederick Damen1, Jin Gao2,3
1Radiology Department, University of Illinois at Chicago, Chicago, Illinois, USA.
Magnetic Resonance in Medicine
|November 9, 2021
Summary
Z-spectrum imaging can accurately measure temperature changes by monitoring proton resonance frequency shifts. This technique is reliable in both muscular and fatty tissues, independent of phase artifacts.
Area of Science:
- Biomedical Imaging
- Magnetic Resonance Imaging
- Temperature Measurement
Background:
- Z-spectrum imaging is a novel MRI technique for measuring fat-water fraction.
- It detects simultaneous fat and water resonances.
- Incorporating a binomial pulse enhances spectral selectivity for temperature monitoring.
Purpose of the Study:
- To evaluate Z-spectrum imaging for temperature change measurement.
- To test the hypothesis in phantoms and in vivo.
- To assess the technique's reliability in different tissue types.
Main Methods:
- Consecutive image acquisition after saturating over a range of frequency offsets.
- Utilized a binomial pulse module with two sinc-shaped pulses of opposite phase.
- Tested in aqueous and cream phantoms, and in healthy mice under thermal challenge.
Main Results:
- Water resonance shifted downfield during heating experiments.
- Temperature changes were quantified by fitting the resonance shift to a sine function.
- Z-spectrum imaging results showed linear correlation with T1 mapping and spoiled GRE phase differences.
Conclusions:
- Z-spectrum imaging provides reliable temperature change measurements.
- The technique is independent of phase artifacts, applicable in mixed tissues.
- Demonstrated efficacy in both muscular and fatty tissues.

