Brown tumor in the palate associated with primary hyperparathyroidism

Area of Science:

• Oral Pathology
• Endocrinology
• Oncology

Background:

• Primary hyperparathyroidism is a condition characterized by excessive parathyroid hormone production.
• Brown tumors are benign bone lesions that can occur in hyperparathyroidism due to bone resorption.
• Oral manifestations of endocrine disorders are uncommon but significant for early diagnosis.

Observation:

• A patient presented with a brown tumor on the hard palate.
• Oral findings and clinical history suggested primary hyperparathyroidism.
• Biochemical tests confirmed elevated parathyroid hormone levels.

Findings:

• Surgical excision of a parathyroid adenoma was performed.
• Post-operative normalization of metabolic parameters was achieved.
• One-year follow-up revealed significant reduction in palatal tumor size and partial regeneration of lamina dura.

Implications:

• This case highlights the importance of considering endocrine disorders in the differential diagnosis of oral lesions.
• Early detection and treatment of primary hyperparathyroidism can prevent or reverse bone pathology.
• Management of parathyroid adenomas can lead to favorable outcomes for associated oral manifestations.