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Updated: Oct 14, 2025

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Isolated late intradural cauda equina metastasis of renal cell carcinoma
Sundus Ali1, Adnan Qasim1, Rahmatullah Salah1
1Department of Neurosurgery, King Edward Medical University, Lahore, Mayo Hospital, Lahore, Punjab, Pakistan.
Background:
The cauda equina (CE) is the most common site for intradural extramedullary metastasis from systemic malignancies such as lung, breast, and thyroid carcinomas. However, renal cell carcinomas (RCC), with their high metastatic potential, are rarely responsible for CE metastatic lesions. Here, we report an intradural cauda equina mass, as the first and only site of metastasis of a renal cell carcinoma.
Case Description:
A 55-year-old female had undergone a left nephrectomy for renal cell carcinoma 8 years ago. She now presented with a unifocal renal cell metastasis to the CE. As such metastases are rare, establishing the correct pathological diagnosis proved to be a challenge.
Conclusion:
The cauda equina was the first and only site of an 8-year-delayed metastasis attributed to a renal cell carcinoma.
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