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Updated: Oct 14, 2025

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
Published on: March 13, 2012
A case of Bertolotti's syndrome as a cause of sciatica
Sarah Kawtharani1, Shadi Abdelatif Bsat1, Mohamad El Housheimy1
1Department of Neurosurgery, American University of Beirut Medical Center, Hamra, Beirut, Lebanon.
Background:
Bertolotti's syndrome (i.e., varying extent of fusion between the last lumbar vertebra and the first sacral segment) or lumbosacral transitional vertebrae is a rare cause of back pain. Notably, this syndrome is one of the differential diagnoses for patients with refractory back pain/sciatica.
Case Description:
A 71-year-old male presented with low back pain of 3 years duration that radiated into the right lower extremity resulting in numbness in the L5 distribution. He then underwent a minimally invasive approach to resect the L5 "wide" transverse process following the CT diagnosis of Bertolotti's syndrome. Prior to surgery, patient reported pain that was exacerbated by ambulation that resolved post-operative.
Conclusion:
Bertolotti's syndrome is one of the rare causes of sciatica that often goes undiagnosed. Nevertheless, it should be ruled out for patients with back pain without disc herniations or other focal pathology diagnosed on lumbar MR scans.

