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Related Experiment Video

Updated: Oct 14, 2025

Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus
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Sclerotherapy for Aneurysmal Bone Cyst: A Single-Center Experience.

Deepak Kumar1, Sanjeev Kumar1, Dharmendra Kumar1

  • 1Orthopedic Surgery, King Georges Medical University, Lucknow, IND.

Cureus
|November 10, 2021
PubMed
Summary

Sclerotherapy effectively heals aneurysmal bone cysts (ABC) with high ossification rates and significant pain reduction. This minimally invasive treatment offers a promising alternative to surgery for ABC patients.

Keywords:
aneurysmal bone cystclinical efficacycomplicationspolidocanol 3%sclerotherapy

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Area of Science:

  • Orthopedics
  • Interventional Radiology
  • Oncology

Background:

  • Aneurysmal bone cysts (ABC) are benign, expansile bone lesions.
  • Sclerotherapy presents a minimally invasive alternative to surgical intervention for ABC treatment.

Purpose of the Study:

  • To evaluate the radiological efficacy of sclerotherapy in healing ABC cavities.
  • To assess the clinical effectiveness of sclerotherapy regarding pain, recurrence, and complications.

Main Methods:

  • A prospective study included 26 patients with biopsy-proven ABC treated with intralesional polidocanol 3% under fluoroscopic guidance.
  • Radiological assessment of ossification via X-ray and pain evaluation using the Visual Analog Scale (VAS).

Main Results:

  • Complete ossification was observed in 92.3% of patients; partial ossification in 7.7%.
  • 70% of patients were pain-free at three months, with significant VAS score improvement.
  • Two recurrences were successfully managed with repeat injections.

Conclusions:

  • Sclerotherapy is an effective and minimally invasive treatment for ABC, especially for deep or surgically challenging lesions.
  • Percutaneous polidocanol 3% injection under fluoroscopic guidance offers a favorable risk/benefit ratio.
  • Sclerotherapy is a viable alternative treatment option for aneurysmal bone cysts.