Related Experiment Video
Updated: Oct 13, 2025
07:03
Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
Published on: February 15, 2022
1.6K
Acute Kidney Failure During SARS-CoV-2
Chantal Fortin1, Anne Boucher2
1an Adult Specialized Nurse Practitioner and an Associate Professor, University of Montréal, Integrated University Health and Social Services Center, Maisonneuve- Rosemont Hospital, Transplant Clinic, Ambulatory Centre, Montréal, Quebec, Canada.
Summary
Acute kidney injury (AKI) during COVID-19 infection increases patient mortality. Early detection and nursing interventions are crucial for managing COVID-19-related kidney injury and improving outcomes.
Area of Science:
- Nephrology
- Infectious Diseases
- Critical Care Medicine
Background:
- COVID-19 infection is linked to a higher risk of acute kidney injury (AKI), impacting patient morbidity and mortality.
- AKI can manifest at any stage of COVID-19, necessitating vigilant clinical assessment and risk factor evaluation.
- Understanding the pathophysiology and risk factors for COVID-19-associated AKI is vital for timely intervention.
Purpose of the Study:
- To review current data on the mechanisms of kidney injury caused by the SARS-CoV-2 virus.
- To identify key risk factors associated with the development of AKI in COVID-19 patients.
- To propose nursing-led strategies for the detection, prevention, and management of AKI in this population.
Main Methods:
- Literature review of recent studies on COVID-19 and kidney injury.
- Analysis of risk factors including pre-existing chronic kidney disease, obesity, and disease severity.
- Identification of potential genetic susceptibilities.
Main Results:
- Pre-existing chronic kidney disease, obesity, and severe COVID-19 presentation are identified as significant risk factors for AKI.
- Patients developing AKI during severe COVID-19 may experience worse outcomes compared to non-COVID-19 AKI patients.
- Genetic factors may contribute to the susceptibility of developing AKI in the context of COVID-19.
Conclusions:
- Early detection, risk factor management, and prompt diagnosis are essential for preventing complications of COVID-19-related AKI.
- Nurses play a critical role in the detection, prevention, and treatment of AKI in COVID-19 patients.
- Healthcare facilities must prepare for the long-term burden of survivors with AKI associated with COVID-19, informing resource planning and future preparedness.
Related Concept Videos
01:22Acute Kidney Injury I: Introduction
134
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
134
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
82
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
82
01:29Acute Kidney Injury II: Pathophysiology
197
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
197
01:29Acute Kidney Injury III: Clinical Manifestations
188
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
188
01:20Acute Kidney Injury V: Interprofessional Care
68
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
68
01:27Dialysis
623
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
623